Experimental model


All relevant publications

Experimental model

Virus-host interaction

Published by Eike Steinmann

Hepatitis E virus (HEV) primarily causes liver infections, but emerging evidence suggests that it can also affect other organs, including the nervous system, leading to a range of neurological disorde...


Experimental model

Published by Lin Wang

The rapid establishment of a viral infection animal model is valuable for pathogenesis studies and testing of vaccines and therapeutic agents. Common approaches may require inoculation of experimental...


Experimental model

Immunity

Published by Qiyu He, Lin Wang

Chronic hepatitis E mostly occurs in organ transplant recipients and can lead to rapid liver fibrosis and cirrhosis. Previous studies found that the development of chronic hepatitis E virus (HEV) infe...


Experimental model

Published by Lin Wang, tianxu liu

Viral hepatitis caused by hepatitis A, B, C, D and E viruses (HAV to HEV) is of great concern worldwide because of the associated burden of illness and death. However, immunocompetent small animal mod...


Experimental model

Published by Siddharth Sridhar

Convenient small animal models of chronic hepatitis E are necessary for investigating the course of HEV infection in immunocompromised persons. Currently available small animal models for this purpose...


Experimental model

Published by Siddharth Sridhar

Hepatitis E virus (HEV) is challenging to cultivate in vitro. Replication is often weak and highly strain dependent. Also, viruses released from cells in culture are cloaked in cell-derived envelopes ...


Experimental model

Published by chunnan liang

At least 20 million hepatitis E virus (HEV) infections occur annually. Hepatitis E is generally acute and self-limiting. However, chronic hepatitis E has gained more attention worldwide and has been r...


Experimental model

Published by Loan Dao Thi

The heterogenous nature of hepatitis E virus (HEV) infections poses clinical challenges. Tropical HEV genotype (GT)1 & 2 infections can lead to acute liver failure, especially in pregnant women, w...


Experimental model

Published by Lin Wang

Hepatitis E virus (HEV) has become the emerging cause of viral hepatitis in humans worldwide with genotype 1-4 (HEV1-4) contributing to most cases in humans. Although most HEV infections are acute and...


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EVENTS

2025-01-18

International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)