Research Papers


All research highlights

Virology

Published by Toni Lusie Meister, Eike Steinmann

Hepatitis E virus (HEV) has increasing prevalence worldwide with over three million infections every year. HEV is the causative agent of hepatitis E in humans and is the leading cause of enterically t...


Virology

Published by Bo Wang, Xiang-Jin Meng

Hepatitis E virus (HEV) infection in pregnant women has a high incidence of developing fulminant hepatic failure (FHF) with significant mortality. Multiple amino acid changes in the genome of HEV-1 ar...


Public health

Published by Mathias Schemmerer

Orthohepevirus A, also known as the hepatitis E virus (HEV), is endemic in Europe. HEV is divided into eight genotypes (HEV-1 to -8). Zoonotic HEV-3 is predominant in Europe and can further be differe...


Animal reservoir

Published by Javier Caballero Gómez, Antonio Rivero, Antonio Rivero-Juarez

The Iberian lynx (Lynx pardinus) is still the most endangered felid species in the world, although different projects, including EU LIFE-Nature projects, have been launched since 2000s to save the Ibe...


Experimental model

Published by Siddharth Sridhar

Hepatitis E virus (HEV) is challenging to cultivate in vitro. Replication is often weak and highly strain dependent. Also, viruses released from cells in culture are cloaked in cell-derived envelopes ...


Experimental model

Published by chunnan liang

At least 20 million hepatitis E virus (HEV) infections occur annually. Hepatitis E is generally acute and self-limiting. However, chronic hepatitis E has gained more attention worldwide and has been r...


Antiviral agent

Published by Mara Klöhn, Eike Steinmann

Every year, an estimated 20 million people become infected with HEV, resulting in 3.3 million acute cases and approximately 70,000 deaths annually, making HEV the leading cause for acute viral hepatit...


Diagnostics

Published by Jian Wu, Ze Xiang

Although hepatitis E virus (HEV) infection is usually asymptomatic and results in a self-limited disease with low mortality, some patients, particularly pregnant women, the elderly, and people with pr...


Virus-host interaction

Published by Debin Tian, Xiang-Jin Meng

HEV infection is associated with nerve root and plexus sequelae, such as Guillain-Barré syndrome and neuralgic amyotrophy, in a significant proportion of HEV-infected individuals worldwide. Additiona...


Public health

Published by Maria Belen Pisano

The hepatitis E virus (HEV) causes acute hepatitis, which can progress to chronicity in immunosuppressed patients. Although it is transmitted mainly by the fecal-oral or zoonotic routes, there is curr...


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EVENTS

2025-01-18

International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)