Research Papers


All research highlights

Virology

Published by Qiang Ding, Xiaohui Ju

Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis in the world. There are no direct-acting antivirals for HEV treatment. The mechanism of HEV replication, especially host facto...


Hepatology

One health

Published by Dionysios Kogias

Hepatitis E virus (HEV), a common cause of viral hepatitis in developing countries, is mainly transmitted via the fecal–oral route, but also may be a prevalent hospital-transmitted agent among patie...


Virology

Published by Zongdi Feng, Arash Grakoui

HEV has a single capsid protein encoded by its open reading frame (ORF) 2. Recent studies have shown that most of the ORF2 protein found in the circulation of HEV-infected patients is not associated w...


Clinical feature

Published by Ibrahim M. Sayed, Haidi Karam-Allah Ramadan

Extrahepatic disorders such as renal or neurological manifestations, cryoglobulinemia, and pancreatitis were reported with HEV infection. These disorders were reported mainly during HEV-3 or HEV-4 chr...


Animal reservoir

Published by Fabian Lean

The ferret is commonly used as an animal model for studying viral diseases, including the flu and SARS-CoV-2. However, compared to other animals used in experimental studies, we don't know as much abo...


Virus-host interaction

Published by Hassan Mahsoub, Xiang-Jin Meng

Hepatitis E virus (HEV) causes adverse clinical outcomes in pregnant women, including preterm delivery, miscarriage, stillbirth, fulminant hepatic failure (FHF), and mortality. The underlying mechanis...


Virology

Published by Bo Wang, Xiang-Jin Meng

Hepatitis E virus (HEV) causes chronic hepatitis E that requires antiviral therapy in immunosuppressed individuals. Ribavirin (RBV) is the main therapeutic option for chronic hepatitis E as an off-lab...


Public health

Published by Eike Steinmann, Yannick Brüggemann

In order to assess the risk of transmission of a given pathogen and determine the most appropriate hygiene measures, detailed information about its survival on different surfaces and susceptibility to...


Virus-host interaction

Published by Eike Steinmann

Although hepatitis E virus (HEV) is the most common cause for acute viral hepatitis with more than 20 million cases per year and 70 000 deaths annually, very little is known about the life cycle of ...


Vaccine

Published by Joakim Øverbø, Asma Aziz

Hepatitis E virus (HEV) is a major cause of acute viral hepatitis and is particularly harmful in low-income countries where it can cause large epidemics with a disproportionate toll on pregnant women ...


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EVENTS

2025-01-18

International Joint Meeting on Viral Infections of the Liver and the Heart (2025)
Day two of this symposium will place a special emphasis on Hepatitis E — a virus that, despite being the most common cause of viral hepatitis, offers a valuable opportunity for further research and understanding. Venue: Cantinerie Berlin Gustav-Meyer-Allee 25 13355 Berlin, Germany. Organisers: Prof. Dr. Jens Kurreck, Dr. rer. nat. Daniel Todt, Prof. Dr. med. Heiner Wedemeyer, More information: Medizinische Hochschule Hannover : International DFG/DZIF Joint Meeting on Viral Infections of the Liver and the Heart (mhh.de)